Chagas Disease

What is Chagas disease? Also called American trypanosomiasis, Chagas disease is an infection caused by the parasite Trypanosoma cruzi. Chagas disease primarily affects low income people living in rural areas. It is estimated that 16-18 million people are infected with Chagas disease; of those infected, 50,000 will die each year. Chagas disease is locally transmitted in Argentina, Belize, Bolivia, Brazil, Chile, Colombia, Costa Rica, Ecuador, El Salvador, French Guiana, Guatemala, Guyana, Honduras, Mexico, Nicaragua, Panama, Paraguay, Peru, Suriname, Uruguay, and Venezuela.

How do I get it? Small critters called “kissing bugs” that live in cracks and holes of substandard housing primarily found in South and Central America. Insects become infected after biting an animal or person who already has Chagas disease. Infection is spread to humans when an infected bug deposits feces on a person’s skin, usually while the person is sleeping at night. The person often accidently rubs the feces into the bite wound, an open cut, the eyes, or mouth.

How do I know if I have it? There are three stages of infection with Chagas disease; each stage has different symptoms. Some people may be infected and never develop symptoms. Acute symptoms only occur in about 1% of cases and most people infected do not seek medical attention. The most recognized symptom of acute Chagas infection is the Romaña’s sign, or swelling of the eye on one side of the face, usually at the bite wound or where feces were rubbed into the eye. Other symptoms are usually not specific for Chagas infection. These symptoms may include fatigue, fever, enlarged liver or spleen, and swollen lymph glands. Sometimes, a rash, loss of appetite, diarrhea, and vomiting occur. In infants and in very young children with acute Chagas disease, swelling of the brain can develop in acute Chagas disease, and this can cause death. In general, symptoms last for 4-8 weeks and then they go away, even without treatment.

What should I do if I have Chagas disease? See your doctor for a blood tests to determine whether there are parasite or antibodies in your blood. Medication for Chagas disease is usually effective when given during the acute stage of infection. Once the disease has progressed to later stages, medication may be less effective. In the chronic stage, treatment involves managing symptoms associated with the disease.

How can I prevent Chagas disease? Avoid sleeping in thatch, mud, or adobe houses, and use insecticides to kill insects and reduce the risk of transmission. There is neither a vaccine nor recommended drug available to prevent Chagas disease.